Pharmaceutical

Transdermal drug delivery

Transdermal drug delivery is an approach employed to deliver drugs through the skin for therapeutic applications as an alternative to injections, oral pills and other drug delivery methods such as transmucosal and inhalation. Transdermal drug delivery can be defined as the passage of a substance, such as a drug, from the skin through its various layers into the bloodstream.

Benefits of Transdermal drug delivery:

• Eliminates potential pain associated with injections
• No first pass metabolism in liver
• Eliminates gastrointestinal side effect
• Improves patient compliance due to simpler, pain free delivery
• Potential for home administration

Active Iontophoresis Transdermal Drug Delivery System

The Transcu active iontophoresis transdermal drug delivery system rely on the principle of iontophoresis which includes the use of external electrical sources to deliver drugs non-invasively through the skin, controlling the rate and duration of drug delivery. Iontophoresis is the application of an electric power source that charges the drug substance and facilitates the movement of these charged drugs to move into the skin.

Advantages of the Transcu active transdermal drug delivery systems over existing products and devices include the following:

• Use of unique polymers to improve contact with skin and the rate and reliability of drug delivery
• Use of stable and safe electrode materials for iontophoretic delivery
• Streamlined product design for ease of use and improved patient compliance
• More rapid onset of drug delivery
• Potential for better control over the rate of delivery
• Minimal skin irritation and enhanced safety

Passive Ionic Transdermal Drug Delivery System

The Transcu passive ionic transdermal drug delivery system is a simple, relatively inexpensive and optimised enhancer patch system that can accelerate the delivery of larger 'ionic' or electrically charged drugs which other conventional systems cannot effectively deliver. Conventional passive delivery systems are only effective for the delivery of smaller, uncharged drugs.

Advantages of the Transcu passive delivery systems over existing products and devices include the following:

• Faster drug transport
• Enhanced safety
• More rapid onset of drug delivery